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  1. Introducing the new synthetic Cannabinoids metabolism and strategies that will enable you best Identify Optimal marker Metabolites.
The Synthetic cannabinoids SCs were initially developed as pharmacological tools to study the endocannabinoid system and as novel pharmacotherapies, but are now highly abused. The abuse of such products is a serious public health and social problem throughout the world and it is highly challenging to identify which SC was consumed by the drug abusers, a necessary step to tie adverse health effects to the new drug’s toxicity. Two intrinsic properties complicate SC identification, their often rapid and extensive metabolism, and their generally high potency relative to the natural psychoactive Δ9-tetrahydrocannabinol in cannabis.

Like its research chemical cathinone predecessors, it is has gained notoriety for its tendency to induce compulsive redosing and addictive behaviours in a large percentage of its users as well the ability to readily induce delusional states and psychosis when abused.

 

 

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